respondents with no education had poor knowledge on malaria. There is a need to improve education on malaria with active participation of women and improve malaria surveillance that will lead to malaria eradication.The intense global efforts are directed towards development of vaccines to halt the COVID-19 virus pandemic. There are 160 candidate vaccines under clinical trials across the world using different molecular targets and techniques. This race for the vaccine has several challenges and ethical issues like compressed timelines, generation and proper management of resources and finances, risks to the participating volunteers due to curtailed research trial processes, geopolitical contentions, misinformation through social media and parallel race with drugs. We feel that the fundamental principles of ethics autonomy, beneficence, non-maleficence and justice should not be violated in this hastened vaccine development process. We recommend constitute a Consortium on a global platform to formulate, provide and monitor a comprehensive ethical umbrella to the process of vaccine development.The etiology of cryptic pregnancy has not been fully elucidated and there exist misconceptions about this phenomenon in our contemporary Nigerian society. This case presents the first case report of cryptic pregnancy in sub-Saharan Africa. A case of a 19 year old overweight female student who presented to the sick bay at 01 30 hours with a 3-day history of lower back pain, abdominal discomfort and constipation. At the sick bay the general practitioner on call asked if she was pregnant and she vehemently said no, recounting that she sees her menstruation regularly. https://www.selleckchem.com/products/FK-506-(Tacrolimus).html Abdominal examination however, revealed a gravid uterus of about 36 weeks and vaginal examination showed a fully dilated cervix. She was surprised, terrified and confused and only remembered having unprotected sexual intercourse many months earlier. Barely two hours later, she gave birth via spontaneous vaginal delivery, to a live female infant at 03 14 hours. This case emphasizes the need for general practitioners and specialists in sub-Saharan Africa to be aware of the phenomenon of cryptic pregnancy, which involves women not being conscious of their gravid state until final weeks of gestation or at delivery, to reduce neonatal and maternal complications.hand hygiene (HH) is an effective measure to reduce healthcare-associated infections and the growing burden of antimicrobial resistance. There is a need to understand the perceptions of healthcare workers towards its practice and the use of alcohol-based hand rubs (ABHR) to make recommendations to promote HH. Our study aimed to explore the perceptions of Nigerian healthcare workers towards HH and the use and availability of ABHR to suggest potential interventions to improve its practice as qualitative evidence in this field is limited in Nigeria.
a qualitative study design was utilized to understand the perceptions of healthcare workers towards HH and the use of ABHR at Adeoyo Maternity Hospital, Ibadan, Nigeria. Purposive sampling was used to recruit nineteen healthcare workers who were interviewed. Thematic content analysis was used to analyze the data generated.
five themes emerged including discrepancies in what constitutes HH practice as participants, motivation for HH practice, a good knowledge oforkers. Hospitals should also ensure adequate provision of resources for hand hygiene and institute a continuous monitoring and feedback program to evaluate compliance with regulations.the impact of prenatal maternal affectivity on infant development is poorly documented in Africa. The purpose of our study is to determine the relationship between mother feelings about pregnancy and childbirth, infant´s behavior and development.
one hundred and twenty mothers aged 28,4 years (± 12,18 years) with their babies aged 38,70 months (± 19,19) were enrolled in a cross-sectional study based on an interview and questionnaire on maternal affectivity, mother-child relationship, infant´s behavior and psychosocial development. Maternal depression was assessed by Edinburgh (EPDS), Goldberg Depression and anxiety scales and DSM-IV (MINI) criteria. Chi-square and Mann-Whitney were used to describe the relationship between maternal affectivity and infant's behavior and health.
unintended pregnancy and fear of childbirth were associated with high anxiety and depression scores. Negative feelings about pregnancy were associated with the lack of social support by the child´s father (0.0110), stress when women were pregnant with a frustrated child (p=0.046), difficult consolability (p&lt;0.001), poor baby's health (p=0.010), infant non-affiliative behavior (p=0.034) and depression identified by using EPDS (p=0.028). Fear of childbirth was associated with delayed or absent responses to infant´s signals (p=0.002) and stress if they were carrying a frustrated baby (p=0.020).
negative feelings during pregnancy are predictive of maternal depression, mother-child relationship disorders, infant´s health and development.
negative feelings during pregnancy are predictive of maternal depression, mother-child relationship disorders, infant´s health and development.Erythrophagocytosis by blast cells is due to hyperactivation of blast cells. Erythrophagocytosis is associated with T cell myeloid hemopathies (8;16). This study shows an exceptional case of erythrophagocytosis by blast cells in a patient with acute T-lymphoblastic leukemia without cytogenetic abnormalities. We here report the case of A.Z, aged 19 years presenting with febrile syndrome with dizziness and phosphenes, tumor syndrome with amygdala and gingival hypertrophy. Blood count revealed hyperleukocytosis (399.5 G/L), with aregenerative anemia (Hb 9.3 g/dl) and thrombocytopenia (platelet count 40 g/L). Myelogram showed 90% of blast cells (MPO-negative) with erythrophagocytosis by blast cells images. Immunophenotyping confirmed T-cell LAL. Cytogenetic analysis was normal. Erythrophagocytosis by blast cells in patients with T-cell LAL appears to be a separate entity, hence the importance of images on diagnosis, prognosis and treatment of T-cell LAL.